Purification of Copper Radioisotopes for Medical Applications: Chromatographic Methods and Challenges

Separation & Purification Reviews

2024 | journal-article

Fully Automated Production of [68Ga]GaFAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets

International Journal of Molecular Sciences

2023 | journal-article

Fully Automated Production of [68Ga]FAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets

2023 | preprint

Production of GMP-Compliant Clinical Amounts of Copper-61 Radiopharmaceuticals from Liquid Targets

Pharmaceuticals

2022 | journal-article

Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA

EJNMMI Radiopharmacy and Chemistry

2021 | journal-article

GMP-Automated Purification of Copper-61 Produced in Cyclotron Liquid Targets: Methodological Aspects

Current Radiopharmaceuticals

2021 | journal-article

Copper-61 from liquid targets: optimized purification for GMP labelling

Nuclear Medicine and Biology

2021 | journal-article

Anticancer Activity and Mode of Action of Copper(II)‐Bis(thiosemicarbazonato) Complexes with Pendant Nitrogen Heterocycles

European Journal of Inorganic Chemistry

2021 | journal-article

Copper-64 Chloride Exhibits Therapeutic Potential in Three-Dimensional Cellular Models of Prostate Cancer

Frontiers in Molecular Biosciences

2020 | journal-article

A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles

Nanoscale

2019 | journal-article

Radiobiological Characterization of ⁶⁴CuCl₂ as a Simple Tool for Prostate Cancer Theranostics

Molecules

2018 | journal-article

Automated Purification of Radiometals Produced by Liquid Targets

Instruments

2018 | journal-article

Process for producing Gallium-68 through the irradiation of a solution target

2018 | patent

Process for producing gallium-68 through the irradiation of a solution target

2017 | patent

Production of copper-64 and gallium-68 with a medical cyclotron using liquid targets

Modern Physics Letters A

2017 | journal-article

Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes

Journal of Inorganic Biochemistry

2017 | journal-article

Cyclotron production of Ga-68 for human use from liquid targets: From theory to practice

2017 | conference-paper

Fast and cost-effective cyclotron production of 61Cu using a natZn liquid target: an opportunity for radiopharmaceutical production and R&D

Dalton Transactions

2017 | journal-article

Process for producing gallium-68 through the irradiation of a solution target

2016 | patent

Production of 68Ga in a mid-energy cyclotron: the solution is in the target

Endocrine Abstracts

2016 | journal-article

GMP production of 68Ga-labelled DOTA-NOC on IBA Synthera

Journal of Radioanalytical and Nuclear Chemistry

2015 | journal-article

Synthesis of (R)-[N-Methyl-11C]PK11195

Radiochemical Syntheses

2015 | book-chapter

68Ga-labelled RGD peptides for imaging of avß3 integrin expression in neovasculature

World Molecular Imaging Congress

2014 | conference-poster

Assessing GBM-induced microglia activation with [11C]PK11195

European Molecular Imaging Meeting

2014 | conference-poster

GMP production of gallium-68 peptides on a commercial synthesiser

17th European Symposium on Radiopharmacy and Radiopharmaceuticals

2014 | conference-poster

Optimisation of synthesis, purification and reformulation of (R)-[N-Methyl-11C]PK11195 for in vivo PET imaging studies

2013 IEEE 3rd Portuguese Meeting in Bioengineering (ENBENG)

2013 | conference-paper

Production optimization of 68Ga-DOTA-NOC for routine synthesis

Society of Nuclear Medicine and Molecular Imaging’s (SNMMI) Annual Meeting

2013 | conference-poster

Optimisation of synthesis, purification and reformulation of (R)-[N-methyl-11C] PK11195 for in vivo PET imaging studies

2012 | dissertation-thesis

Optimisation of synthesis, purification and reformulation of (R)-[N-methyl-¹¹C] PK11195 for in vivo PET imaging studies

2012 | dissertation-thesis

Synthesis optimization of pittsburgh compound B by the captive solvent method

2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)

2012 | conference-paper

Synthesis optimization of pittsburgh compound B by the captive solvent method

2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG)

2012 | conference-paper

EP3101660 (A1) - Process for producing gallium-68 through the irradiation of a solution target

| patent