Algoritmi | User | Antero José Pena Afonso de Abrunhosa
Antero José Pena Afonso de Abrunhosa
Antero José Pena Afonso de Abrunhosa
Personal Email
antero@pet.uc.ptOrcid
0000-0002-4145-854XResearcher ID
FCT Public Key
Ciência ID
2E1B-49C3-207DGoogle Scholar
About Me 
First degree in Biochemistry (1992) and MSc in Biomedical Engineering (1996) from the University of Coimbra, Portugal. PhD work under Prof. Terry Jones’ supervision at the MRC - Cyclotron Unit, Hammersmith Hospital in London, UK (2002). From 2000 to 2009, helped to design and supervised the construction of the Institute for Nuclear Sciences Applied to Health (ICNAS) a leading facility in Portugal for Nuclear Imaging based at the University of Coimbra. He is the current Director of the Institute and the head of the Radiochemistry Laboratory (RCL). ICNAS has extensive expertise in the development of radiopharmaceuticals for Oncology, Cardiology and Neuroscience and is fully equipped for clinical imaging (2 PET/CT and a 3T MR) as well as pre-clinical studies (including an in-house developed world leading high-resolution small animal PET with 0.3 mm resolution, a 9.4T micro-MRI, an optical imaging system and a photoacoustic tomography device). The RCL hosts 2 cyclotrons (IBA cyclone 18/9 and the first IBA Kiube variable energy, installed in 2019) and is fully licensed as a GMP manufacturing site, currently producing more than 20 different tracers based on 11C, 13N, 18F, 68Ga, 61Cu and 64Cu. The facility is the main supplier of PET radiopharmaceuticals for Portugal, through its subsidiary (ICNAS-P, a company fully owned by the University) that currently has 6 radiopharmaceuticals in the market (FDG, FCH, NaF, 68Ga-DOTANOC, 68Ga-PSMA-11 and F-DOPA). Antero is manager and Head of Production for ICNAS-P from the start. Antero’s research interests include development of targeted probes for molecular imaging, PET, SPECT, radiopharmaceutical development, PET Radiopharmacy and Quality Control, pre-clinical imaging and clinical trials. The Institute is currently participating in more than 30 clinical trials and has recently received approval, by the authorities, of its first investigator driven clinical trial. Regarding technology transfer, Antero promoted the start of 3 spin-off companies from the University of Coimbra, one of them (Fluidomica, Lda) specializes in supplying target solutions for radiometal production. He is a member of the European Pharmacopoeia Group 14 and an Expert in several Technical Committees and Field Missions for IAEA (International Atomic Energy Agency). He currently holds patents in Europe, US and Japan regarding the production of gallium-68 using liquid targets.
Publications (244)
The relation between neuroinflammation, amyloid-β load, grey matter loss and brain activity in visual object recognition regions in Alzheimer's Disease
NeuroImage: Reports
2026 | journal-article
2-[18F]FDG PET/CT identifies metabolic activity linked to myocardial deformation in hypertrophic cardiomyopathy
Meta-Radiology
2025 | journal-article
Molecular targets and the emerging role of copper radionuclides in prostate cancer theranostics
EJNMMI Research
2025 | journal-article
PET/fMRI demonstrates that bariatric surgery may reverse striatal dopaminergic dysfunction in women with obesity
Communications Medicine
2025 | journal-article
Sex-specific cortical networks drive social behavior differences in an autism spectrum disorder model
Translational Psychiatry
2025 | journal-article
GRPR-targeted gold nanoparticles as selective radiotherapy enhancers in glioblastoma
Physics in Medicine & Biology
2025 | journal-article
Unveiling the potential of copper-61 vs. gallium-68 for SSTR PET imaging
European Journal of Nuclear Medicine and Molecular Imaging
2025 | journal-article
First performance evaluation of easyPET.3D, a high-resolution and cost-effective benchtop preclinical PET scanner
EJNMMI Physics
2025 | journal-article
Is Copper-61 the New Gallium-68? Automation and Preclinical Proof-of-Concept of 61Cu-Based Radiopharmaceuticals for Prostate Cancer Imaging
Pharmaceuticals
2025 | journal-article
177Lu-Trastuzumab Radionuclide Therapy: an Effective Approach for Resistant Brain Metastases in HER2+ Breast Cancer
2025 | preprint
Evidence for Neuroplasticity in the Human Brain in Health and Disease: A Systematic Review Focusing on Molecular Imaging Using PET
Neural Plasticity
2025 | journal-article
Improved Production of Novel Radioisotopes with Custom Energy Cyclone® Kiube
Instruments
2024 | journal-article
Purification of Copper Radioisotopes for Medical Applications: Chromatographic Methods and Challenges
Separation & Purification Reviews
2024 | journal-article
Improved Chemical and Radiochemical Synthesis of Neuropeptide Y Y2 Receptor Antagonist N-Methyl-JNJ-31020028 and Preclinical Positron Emission Tomography Studies
Pharmaceuticals
2024 | journal-article
Neurotensin (8-13) and Neuromedin N Neuropeptides Radiolabelling with Copper-64 Produced on Solid or Liquid Targets
Molecules
2024 | journal-article
Development and Testing of an MRI-Compatible Immobilization Device for Head and Neck Imaging
2024 | book-chapter
11C-carboxylations using Grignard reactions for the preparation of [carbonyl 11C]WAY-100635 and [1-11C]Sodium Acetate
2nd CIBIT Meeting
2023 | conference-poster
Negative correlation between cortical tryptophan metabolism and E/I balance in a genetic mouse model of autism spectrum disorders
2nd CIBIT Meeting
2023 | conference-poster
Fully Automated Production of [68Ga]GaFAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets
International Journal of Molecular Sciences
2023 | journal-article
Fully Automated Production of [68Ga]FAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets
2023 | preprint
GMP Production of 89Zr-DFO-Pembrolizumab for Immuno-PET: predicting response in non-small lung cancer
EANM
2023 | conference-poster
Effects of successful percutaneous coronary intervention of chronic total occlusions with demonstrable viability or ischemia: A protocol for a systematic review
2023 | preprint
Imaging platforms to dissect the in vivo communication, biodistribution and controlled release of extracellular vesicles
Journal of Controlled Release
2023 | journal-article
Evaluating Blood-Brain Barrier Permeability Changes during Premetastatic Niche Formation for HER2+ Breast Cancer Brain Metastasis
EACR 2023 Congress
2023 | conference-poster
Antibody and Nanobody Radiolabeling with Copper-64: Solid vs. Liquid Target Approach
Molecules
2023 | journal-article
GMP Production of Copper-64 for antibody and nanobody radiolabeling: liquid vs solid target
25th iSRS
2023 | conference-poster
Textural properties of microglial activation in Alzheimer's disease as measured by (R)-[11C]PK11195 PET
Brain Communications
2023 | journal-article
Synaptic density marker, SV2A, is reduced in autistic adults
INSAR meeting 2023 - International Society for Autism Research
2023 | conference-poster
A neurostimulation and multimodal molecular imaging study of the interhemispheric inhibition/excitation imbalance in stroke
5th International Brain Stimulation Conference
2023 | conference-poster
Imaging of brain tryptophan metabolism and 5-HT1A receptor density in the TSC2 mouse model: Preliminary results
1º CIBIT Anual Meeting
2022 | conference-poster
89Zr-immuno-PET imaging: from liquid target production to imaging
Nuclear Medicine and Biology
2022 | journal-article
Impact of HER2+ brain-tropic breast cancer cells in blood-brain barrier permeability during the pre-metastatic niche formation
Champalimaud Research Symposium 2022
2022 | conference-poster
GMP Production of 89Zr-DFO-Trastuzumab: from chemistry to the clinic
New Modalities in Cancer Imaging and Therapy
2022 | conference-poster
Trastuzumab-resistant HER2+ Brain Tropic Breast Cancer Cells Disrupt the Blood-Brain Barrier: a Potential Route for Brain Drug Delivery
5th ASPIC International Congress
2022 | conference-poster
PET Imaging of the Neuropeptide Y System: A Systematic Review
Molecules
2022 | journal-article
Production of GMP-Compliant Clinical Amounts of Copper-61 Radiopharmaceuticals from Liquid Targets
Pharmaceuticals
2022 | journal-article
Bringing personalized medicine to the next level: RANKL immuno-PET imaging using [64Cu]Cu-NOTA-anti-RANKL-Fab fragments
Nuclear Medicine and Biology
2022 | journal-article
Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments
Pharmaceutics
2022 | journal-article
An RPC-PET brain scanner demonstrator: first results
ArXiv
2022 | journal-article
Bringing personalized medicine to the next level: RANKL immuno-PET imaging using [64Cu]Cu-NOTA-anti-RANKL-Fab fragments
Nuclear Medicine and Biology
2022 | journal-article
Cardiac microcalcification burden: Global assessment in high cardiovascular risk subjects with Na[18F]F PET-CT
Journal of Nuclear Cardiology
2022 | journal-article
Combined Structural MR and Diffusion Tensor Imaging Classify the Presence of Alzheimer's Disease With the Same Performance as MR Combined With Amyloid Positron Emission Tomography: A Data Integration Approach
Frontiers in Neuroscience
2022 | journal-article
Copper-61 as an alternative to Gallium-68 for radiopharmaceutical production: feasibility study and scale-up for clinical doses
Nuclear Medicine and Biology
2022 | journal-article
Mitochondrial and redox modifications in early stages of Huntington's disease
Redox Biology
2022 | journal-article
Mitochondrial and redox modifications in early stages of Huntington¿s disease
redox modifications in early stages of Huntington¿s disease¿. Preprint
2022 | journal-article
Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung Cancer
Cancers
2022 | journal-article
Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis
Small
2022 | journal-article
Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals
EJNMMI Radiopharmacy and Chemistry
2022 | journal-article
Stable [64Cu]-labelled phthalocyanine choline bioconjugate for development of a potential cancer PET probe. In vivo biodistribution evaluation
Journal of Porphyrins and Phthalocyanines
2022 | journal-article
Ventilador mecânico invasivo de emergência resistente e de fácil manutenção
Revista Brasileira de Terapia Intensiva
2022 | journal-article
Zr-89-immuno-PET imaging: from liquid target production to imaging
2022 | conference-poster
Texture Quantification Parameters for Alzheimer's disease diagnosis measured by 11C- (R)- PK11195 PET images
European Journal of Nuclear Medicine and Molecular Imaging - EANM2021 - Annual Congress of the European Association of Nuclear Medicine
2021 | conference-paper
Nanobody-Based Theranostic Agents for HER2-Positive Breast Cancer: Radiolabeling Strategies
International Journal of Molecular Sciences
2021 | journal-article
Automatic classification of idiopathic Parkinson’s disease and atypical Parkinsonian syndromes combining [11C]raclopride PET uptake and MRI grey matter morphometry
Journal of Neural Engineering
2021 | journal-article
NON-INVASIVE SYSTEM FOR MEASURING THE ARTERIAL INPUT FUNCTION FOR PET IMAGING
2021 | patent
Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA
EJNMMI Radiopharmacy and Chemistry
2021 | journal-article
A link between synaptic plasticity and reorganization of brain activity in Parkinson's disease
Proceedings of the National Academy of Sciences
2021 | journal-article
Investigating the Spatial Associations Between Amyloid-β Deposition, Grey Matter Volume, and Neuroinflammation in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
2021 | journal-article
Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA (vol 6, 11, 2021)
EJNMMI Radiopharmacy and Chemistry
2021 | journal-article
Anticancer Activity and Mode of Action of Copper(II)-Bis(thiosemicarbazonato) Complexes with Pendant Nitrogen Heterocycles
European Journal of Inorganic Chemistry
2021 | journal-article
Copper-61 from liquid targets: optimized purification for GMP labelling
Nuclear Medicine and Biology
2021 | journal-article
Preclinical assessment of nanoparticles conjugated with Cu-64-DOTA-PEG-BBN targeting gastrin-releasing peptide receptors
Journal of Nuclear Medicine
2021 | journal-article
Securing Gallium-68 availability with liquid target production on mid-energy cyclotrons: Users' experience and scaling up
European Journal of Nuclear Medicine and Molecular Imaging
2021 | journal-article
Texture Quantification Parameters for Alzheimer's disease diagnosis measured by 11C-(R)-PK11195 PET images
European Journal of Nuclear Medicine and Molecular Imaging
2021 | journal-article
Trimodal Contrast Agents for MRI and Optical Imaging
European Journal of Clinical Investigation
2021 | journal-article
In Vivo Tracking of Extracellular Vesicles by Nuclear Imaging: Advances in Radiolabeling Strategies
International Journal of Molecular Sciences
2020 | journal-article
Copper-64 Chloride Exhibits Therapeutic Potential in Three-Dimensional Cellular Models of Prostate Cancer.
Frontiers in molecular biosciences
2020 | journal-article
GMP automated purification of copper-61 produced in cyclotron liquid targets: methodological aspects.
Current radiopharmaceuticals
2020 | journal-article
Overreduced intracellular state detected in Cu-ATSM brain imaging and fibroblasts from prodromal Huntington disease carriers
European Journal of Clinical Investigation
2020 | journal-article
Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target
Medical Oncology
2020 | journal-article
Prototype of an affordable pressure-controlled emergency mechanical ventilator for COVID-19
2020 | preprint
Aortic valve microcalcification and cardiovascular risk: an exploratory study using sodium fluoride in high cardiovascular risk patients.
The international journal of cardiovascular imaging
2020 | journal-article
Preconditioning mice with osteosarcoma cells-derived secretome promote tumour cells engraftment and lung metastasis development
Tumor Microenvironment (EACR-AACR Basic and Translational Research Conference in partnership with ASPIC)
2020 | conference-poster
Copper-64 based Radiopharmaceuticals as Potential Theranostic Agents
European Journal of Nuclear Medicine and Molecular Imaging
2020 | journal-article
Does global molecular calcium score have a role in HFpEF evaluation?
European Journal of Heart Failure
2020 | journal-article
Overreduced intracellular state detected in Cu-ATSM brain imaging and fibroblasts from prodromal Huntington disease carriers
European Journal of Clinical Investigation
2020 | journal-article
Renal artery wall 18F-NaF activity and glomerular filtration rate: an exploratory analysis in a high cardiovascular risk population
Nuclear medicine communications
2020 | journal-article
Synthesis Optimisation of High Specific Activity Carbon-11 Radiopharmaceuticals for Brain PET Studies
2020 | dissertation-thesis
Secretome derived from osteosarcoma (OS) cells promote tumour cell colonization and lung metastasis formation in pre-treated mice
CIBB Meeting 2019 - Universidade de Coimbra
2019 | conference-poster
Asymmetric Synthesis of a promising [18F]F-DOPA Precursor
XXV Encontro Galego-Portugês de Química, Santiago de Compostela
2019 | conference-poster
Automated microwave-assisted synthesis for PET radiochemistry
XXV Encontro Galego-Portugês de Química, Santiago de Compostela
2019 | conference-poster
Improved nucleophilic synthesis of [18F]F-DOPA using microwave technology
XXV Encontro Galego-Portugês de Química, Santiago de Compostela
2019 | conference-poster
Osteosarcoma-released bioactive factors facilitate lung metastasis by regulating cell adhesion
Seed and Soil: mechanisms of metastasis (2nd joint EACR-MRS conference)
2019 | conference-poster
New Cu-ATSM and Cu-GTSM Derivatives for Cancer Theranostics
NOVA BIOPHYSICA International Congress
2019 | conference-abstract
Potenciais alvos terapêuticos na leucemia mieloblástica aguda - glicólise ou oxidação fosforilativa?
1º Encontro Nacional de Jovens Investigadores em Oncologia
2019 | conference-poster
Glycolysis versus oxidative phosphorylation ¿ Potential therapeutic targets in AML
24º European Hematology Association Congress
2019 | conference-poster
GMP Production of Gallium-68 from a Cyclotron Using Liquid Targets: Regulatory Aspects
22nd International Symposium on Radiopharmaceutical Sciences
2019 | conference-poster
Impact of neurofibromatosis type 1 on early postnatal development: a behavioral approach.
XVI Meeting of the Portuguese Society for Neurocience
2019 | conference-poster
Neural basis for adult cognitive deficits in neurofibromatosis type 1 animal model: Relevance for autism spectrum disorders.
XVI Meeting of the Portuguese Society for Neurocience
2019 | conference-poster
The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing.
Translational medicine @ UniSa
2019 | journal-article
A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss
Human Molecular Genetics
2019 | journal-article
A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles
Nanoscale
2019 | journal-article
A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles
2019 | journal-article
Activated Gold Nanoparticles Conjugated with 68Ga-DOTA-PEG(4)-BBN(7-14) for Targeting Tumours Expressing GRP Receptors
European Journal of Nuclear Medicine and Molecular Imaging
2019 | journal-article
Cardiovascular risk, aortic valve microcalcification and vascular microcalcification: is there a link?
European Heart Journal
2019 | journal-article
Gd- A nd Eu-Loaded Iron Oxide@Silica Core-Shell Nanocomposites as Trimodal Contrast Agents for Magnetic Resonance Imaging and Optical Imaging
Inorganic Chemistry
2019 | journal-article
Labelling and validation of [61Cu]DOTA-NOC for somatostatin receptors imaging
2019 | dissertation-thesis
New chimeric peptides selectively inhibit APPß cleavage decreasing Aß formation and accumulation in AD models
14th International Conference on Alzheimer's & Parkinson's Diseases, Lisbon, Portugal
2019 | conference-poster
PET imaging and in vivo bio-distribution of small extracellular vesicles
European Journal of Clinical Investigation
2019 | journal-article
THE REFERENCE SITE COLLABORATIVE NETWORK OF THE EUROPEAN INNOVATION PARTNERSHIP ON ACTIVE AND HEALTHY AGEING
Translational Medicine @ UniSa
2019 | journal-article
Radiobiological Characterization of 64CuCl2 as a Simple Tool for Prostate Cancer Theranostics
Molecules
2018 | journal-article
Automated Purification of Radiometals Produced by Liquid Targets
Instruments
2018 | journal-article
Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells
Scientific Reports
2018 | journal-article
The excitation/inhibition enigma in a mouse model of the autism spectrum disorder: evidence for distinct phenotypes of hippocampus and prefrontal cortex
11th FENS - Forum of European Neuroscience
2018 | conference-abstract
Therapeutic potential of the metabolic modulator Metformin on osteosarcoma cancer stem-like cells
Cancer Chemotherapy and Pharmacology
2018 | journal-article
Can 11 C-PiB-PET relative delivery R 1 or 11 C-PiB-PET perfusion replace 18 F-FDG-PET in the assessment of brain neurodegeneration?
Journal of Alzheimer's Disease
2018 | journal-article
Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ species
NeuroImage: Clinical
2018 | journal-article
Distributed non-invasive system for measuring the arterial input function in PET
2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings
2018 | conference-paper
Investigação de um detetor não-invasivo para determinar a função de entrada em estudos PET quantitativos
2018 | dissertation-thesis
Optimized non-conventional radioisotopes production with industrial mid-energy cyclotron
European Journal of Nuclear Medicine and Molecular Imaging
2018 | journal-article
qPET: a system for assessing the arterial input function for PET quantification
European Journal of Nuclear Medicine and Molecular Imaging
2018 | journal-article
Deconstructing cancer stem cells: IL-6, G-CSF and Activin-A as mediators of stroma-orchestrated epithelial cells’ dedifferentiation
Cancer Research
2017 | journal-article
Production of copper-64 and gallium-68 with a medical cyclotron using liquid targets
Modern Physics Letters A
2017 | journal-article
Atherosclerotic plaque metabolism in high cardiovascular risk subjects - A subclinical atherosclerosis imaging study with 18F-NaF PET-CT.
2017 | journal-article
Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes.
2017 | journal-article
Assessment of atherosclerotic plaque calcification using F18-NaF PET-CT.
2017 | journal-article
Comparação entre a PET/CT cerebral com 18F-FDG e a fase de perfusão da PET/CT com 11C-PIB
XVI Congresso Nacional de Medicina Nuclear
2017 | conference-abstract
Cyclotron production of Ga-68 for human use from liquid targets: From theory to practice
AIP Conference Proceedings
2017 | conference-paper
Fast and cost-effective cyclotron production of 61Cu using a natZn liquid target: an opportunity for radiopharmaceutical production and R&D
Dalton Transactions
2017 | journal-article
GMP Production of Gallium-68 from a Cyclotron Using Liquid Targets: Regulatory Aspects
Journal of Labelled Compounds
2017 | journal-article
Selective internal radiation therapy: review of the standard operating procedure for selective internal radiation therapy using SIR-Spheres microspheres labelled with Yttrium 90
2017 | dissertation-thesis
Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: In vivo neurospectroscopy and molecular evidence for regional phenotypes
Molecular Autism
2017 | journal-article
Redox and mitochondrial function switches in striatum and cortex of pre-symptomatic and symptomatic Huntington's Disease mouse model
XIX National Congress of Biochemistry
2016 | conference-poster
Redox and mitochondrial functional switches in striatum and cortex of pre-symptomatic and symptomatic Huntington¿s disease mouse model
XIX National Congress of Biochemistry by the Portuguese Society of Biochemistry
2016 | conference-poster
Redox changes and bioenergetic defects in striatum and and cortex of pre-symptomatic and symptomatic Huntington's Disease mice
Society for Neuroscience 46th annual meeting
2016 | conference-poster
Redox changes and bioenergetic defects in striatum and cortex of pre-symptomatic and symptomatic Huntington disease mice.
46th Annual Meeting of Society for Neuroscience (SFN)
2016 | conference-poster
Production of 68Ga in a mid-energy cyclotron: the solution is in the target
Endocrine Abstracts
2016 | journal-article
GABA deficiency in NF1: A multimodal [11C]-flumazenil and spectroscopy study.
2016 | journal-article
18th European Symposium on Radiopharmacy and Radiopharmaceuticals: Salzburg, Austria. 7-10 April 2016.
EJNMMI radiopharmacy and chemistry
2016 | journal-article
Process for producing gallium-68 through the irradiation of a solution target
2016 | other
Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/β-catenin signaling.
2016 | journal-article
68Ga-PSMA PET/CT in Biochemical Relapsed Prostate Cancer Initial Experience
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2016 | conference-paper
68Ga-PSMA PET/CT in Biochemical Relapsed Prostate Cancer Initial Experience
European Journal of Nuclear Medicine and Molecular Imaging
2016 | journal-article
New BACE1 inhibitors decrease Aß production and accumulation in the 3xtg-AD mouse model
XIX National Congress of Biochemistry
2016 | conference-abstract
Pet examination of the monoamine transporter with 11c-beta-cit
Movement Disorders
2016 | journal-article
Production of 68Ga in a mid-energy cyclotron: the solution is in the target
2016 | journal-article
Synthesis of (R)-[N-Methyl-11C]PK11195
Radiochemical Syntheses
2015 | other
AN ULTRA-HIGH RESOLUTION PRECLINICAL POSITRON EMISSION TOMOGRAPHY SCANNER
IEEE Portuguese Meeting on Bioengineering (ENBENG)
2015 | conference-paper
An ultra-high resolution preclinical positron emission tomography scanner
Bioengineering (ENBENG), 2015 IEEE 4th Portuguese Meeting on
2015 | conference-paper
Desenvolvimento de um modelo dosimétrico baseado em medidas de área
2015 | dissertation-thesis
GMP production of 68Ga-labelled DOTA-NOC on IBA Synthera
Journal of Radioanalytical and Nuclear Chemistry
2015 | journal-article
Optimization and Validation of [N-13]-NH3 Production for Clinical Studies of Positron Emission Tomography in the Evaluation of Myocardial Perfusion
IEEE Portuguese Meeting on Bioengineering (ENBENG)
2015 | conference-paper
Optimization and validation of [13N]-NH
Proceedings - 2015 IEEE 4th Portuguese Meeting on Bioengineering, ENBENG 2015
2015 | conference-paper
Radiochemical Syntheses, Volume 2: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production
2015 | other
Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutic Agents
Journal of Heterocyclic Chemistry
2015 | journal-article
Synthesis and biological distribution study of a new carbon-11 labeled porphyrin for PET imaging. Photochemical and biological characterization of the non-labeled porphyrin
Journal of Porphyrins and Phthalocyanines
2015 | journal-article
Synthesis of (R)-[N-Methyl-11C]PK11195
Radiochemical Syntheses
2015 | book-chapter
Synthesis of a new 18F labeled porphyrin for potential application in positron emission tomography. in vivo imaging and cellular uptake
RSC Advances
2015 | journal-article
The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ
Immunology
2015 | journal-article
Assessing GBM-induced microglia activation with [11C]PK11195
EMIM 2014 9th European Molecular Imaging Meeting
2014 | conference-paper
Estudo combinado de PET com [11C]PiB e [18F]FDG na avaliação de doença de Alzheimer
2014 | dissertation-thesis
GABA alterations in patients with Neurofibromatosis type 1: a multimodal 11C-Flumazenil PET and MRS study
WMIC 2014 World Molecular Imaging Congress
2014 | conference-paper
GMP Production of Gallium-68 Peptides on a Commercial Synthesizer
ESRR'14 - 17th European Symposium on Radiopharmacy and Radiopharmaceuticals
2014 | conference-paper
Importância da [11C]-Racloprida no diagnóstico de Síndromes Parkinsónicos com tomografia por emissão de positrões (PET)
2014 | dissertation-thesis
Inflammatory Microenvironment Supports Stem-like Phenotype in Glioblastoma: Cellular Studies with 11C-PK11195
WFNMB 2014 11th Congress of the World Federation of Nuclear Medicine and Biology
2014 | conference-paper
Optimização e Validação da Produção de [13n]-Nh3 para Estudos Clínicos de Tomografia por Emissão de Positrões na Avaliação da Perfusão Miocárdica
2014 | dissertation-thesis
Síntese de macrociclos tetrapirrólicos fluorados. Desenvolvimento de potenciais marcadores para tomografia por emissão de positrões
2014 | dissertation-thesis
Radiosynthesis and in vivo evaluation of a ¹⁸F-labelled styryl-benzoxazole derivative for β-amyloid targeting.
2013 | journal-article
Synthesis of new 18F and 11C porphyrins and their potential application fo in vivo Moleucar Imaging using PET technique
18th European Symposium on Organic Chemistry
2013 | conference-poster
Automated 68Ga-DOTA-NOC production using a commercial synthesizer
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
2013 | conference-paper
Automated 68Ga-DOTA-NOC production using a commercial synthesizer
Journal of Labelled Compounds and Radiopharmaceuticals
2013 | journal-article
Cyclotron Production of 68Ga using a 68Zn-based liquid target
2013 | dissertation-thesis
Image Analysis in Radiology and Nuclear Medicine Automated Analysis of Morfology and Funtion of the Human Brain
IEEE Portuguese Meeting in Bioengineering (ENBENG)
2013 | conference-paper
Image analysis in radiology and nuclear medicine
Bioengineering (ENBENG), 2013 IEEE 3rd Portuguese Meeting in
2013 | conference-paper
Image analysis in radiology and nuclear medicine
3rd Portuguese Bioengineering Meeting, ENBENG 2013 - Book of Proceedings
2013 | conference-paper
Kur CHANNEL BLOCKERS
Physiology and Pathophysiology of the Islets of Langerhans
2013 | journal-article
Optimisation of Synthesis, Purification and Reformulation of (R)-[N-Methyl-C-11]PKll195 for In Vivo PET Imaging Studies
IEEE Portuguese Meeting in Bioengineering (ENBENG)
2013 | conference-paper
Optimisation of synthesis, purification and reformulation of (R)-[N-Methyl-11C]PK11195 for in vivo PET imaging studies
3rd Portuguese Bioengineering Meeting, ENBENG 2013 - Book of Proceedings
2013 | conference-paper
Production optimization of 68Ga-DOTA-NOC for routine synthesis
Journal of Nuclear Medicine
2013 | journal-article
Radiosynthesis of new 18F-labelled meso-tetraphenylporphyrins as potential tracers for in vivo molecular imaging with PET
Journal of Labelled Compounds and Radiopharmaceuticals
2013 | journal-article
Radiosynthesis of new F-18-labelled meso-tetraphenylporphyrins as potential tracers for in vivo molecular imaging with PET
Journal of Labelled Compounds & Radiopharmaceuticals
2013 | journal-article
Synthesis of optimization of [11C] Pittsburgh compound B by the captive solvent method
2013 | dissertation-thesis
473 Hexavalent Chromium, Cancer Stem Cells and Dedifferentiation –a View to a Kill!
European Journal of Cancer
2012 | journal-article
Hexavalent Chromium, Cancer Stem Cells and Dedifferentiation--a View to a Kill!
European Journal of Cancer
2012 | journal-article
Neurodevelopmental Effects of High Magnetic Fields in the Development of an Intact Living Organism: Caenorhabditis elegans
WMIC'12 World Molecular Imaging Congress
2012 | conference-paper
Neuronal and developmental effects of high magnetic fields in the development of an intact living organism: Ceanorhabditis elegans
2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012
2012 | conference-paper
Optimisation of synthesis, purification and reformulation of (R)-[N-methyl-¹¹C] PK11195 for in vivo PET imaging studies
2012 | dissertation-thesis
Optimization of [18F]-FDG production with terminal sterilization by autoclave
Journal of Nuclear Medicine
2012 | journal-article
Optimization of [18F]-FDG production with terminal sterilization by autoclave
Journal of Nuclear Medicine
2012 | journal-article
Positron emitting tracers in pre-clinical drug development
Current Radiopharmaceuticals
2012 | journal-article
Synthesis optimization of pittsburgh compound B by the captive solvent method
2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012
2012 | conference-paper
Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line.
2012 | journal-article
Synthesis of carbon-11 labeled porphyrins as potential cancer biomarkers for PET imaging
XXIII National meeting of Portuguese Society of Chemistry
2011 | conference-poster
Molecular imaging with SPECT as a tool for drug development.
2011 | journal-article
Elucidation of the drug resistance mechanisms of osteosarcoma cancer stem cells with PET tracers
1st Portuguese Meeting in Biomedical Engineering, ENBENG 2011
2011 | conference-paper
Molecular imaging with SPECT and PET in exploratory investigational new drug studies
Drugs of the Future
2011 | journal-article
Molecular imaging with SPECT and PET in exploratory investigational new drug studies
Drugs of the Future
2011 | journal-article
Nanoradioliposomes molecularly modulated to study the lung deep lymphatics drainage.
2010 | journal-article
Aspectos do controlo da qualidade da fluodesoxiglucose num laboratório de produção
Acta Médica Portuguesa
2010 | journal-article
Assessing metabolic activity of Cancer Stem Cells during differentiation with [18 F] FDG
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2010 | conference-paper
Assessing metabolic activity of cancer stem cells during differentiation with [F-18]FDG
European Journal of Nuclear Medicine and Molecular Imaging
2010 | journal-article
Cancer stem cell populations in osteosarcoma: implications for [18F] FDG uptake and response to therapy
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2010 | conference-paper
Cancer stem cell populations in osteosarcoma: implications for [18F]FDG uptake and response to therapy
European Journal of Nuclear Medicine and Molecular Imaging
2010 | journal-article
Nanorradiolipossomas modulados molecularmente para estudar a drenagem linfática profunda pulmonar
Revista Portuguesa de Pneumologia
2010 | journal-article
Osteosarcoma contains a subpopulation of cancer stem-like cells that are highly resistant to radiotherapy.
2010 | journal-article
Radiopharmaceuticals
Nuclear Medicine Physics. Series: Series in Medical Physics and Biomedical Engineering, ISBN: 978-1-58488-795-9. Taylor & Francis, Edited by J de Lima, pp. 95-132
2010 | journal-article
Role of Cancer Stem Cells in [18F]FDG Uptake and Therapy Response in Osteosarcoma
2010 World Molecular Imaging Congress
2010 | conference-paper
Síntese de [18F]-FDG no módulo synthera
Acta Médica Portuguesa
2010 | conference-paper
Śıntese e purificação de [11C]-raclopride
Acta Médica Portuguesa
2010 | journal-article
P-glycoprotein versus MRP1 on transport kinetics of cationic lipophilic substrates: a comparative study using [99mTc]sestamibi and [99mTc]tetrofosmin.
2009 | journal-article
Imaging multidrug resistance in osteosarcoma: A pre-clinical approach using an orthotopic animal model
IFMBE Proceedings
2009 | conference-paper
Nanoradioliposomes molecularly modulated to study the lung deep lymphatic drainage
2009 | journal-article
Nanoradioliposomes molecularly modulated to study the lung deep lymphatic drainage,Nanorradiolipossomas modulados molecularmente para estudar a drenagem linfática pulmonar profunda
Revista Portuguesa de Pneumologia
2009 | journal-article
Re and Tc Tricarbonyl Complexes with Established Affinity for 5-HT1A Receptors: a 3D QSAR study
2009 World Molecular Imaging Congress
2009 | conference-paper
Effects of high magnetic fields in the development of the organism Caenorhabditis Elegans
2008 World Molecular Imaging Congress
2008 | conference-paper
Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using 99mTc-sestamibi.
2007 | journal-article
Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using 99mTc-sestamibi
European journal of nuclear medicine and molecular imaging
2007 | journal-article
Molecular imaging of multidrug resistance in an orthotopic model of osteosarcoma
Modern Pathology
2007 | journal-article
Molecular imaging of multidrug resistance in an orthotopic model of osteosarcoma
Laboratory Investigation
2007 | journal-article
[Tc-99m] Sestamibi vs.[Tc-99m] Tetrofosmin for functional assessment of P-glycoprotein and MRP1-mediated drug resistance in SCLC cell lines
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2007 | conference-paper
[Tc-99m]Sestamibi vs. [Tc-99m]Tetrofosmin for functional assessment of P-glycoprotein and MRP1-mediated drug resistance in SCLC cell lines
European Journal of Nuclear Medicine and Molecular Imaging
2007 | journal-article
Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies.
2006 | journal-article
Molecular imaging of multidrug resistance in an orthotopic model of osteosarcoma
EUR J NUCL MED MOL I
2006 | journal-article
Molecular imaging of multidrug resistance in an orthotopic model of osteosarcoma
European Journal of Nuclear Medicine and Molecular Imaging
2006 | journal-article
Multidrug resistance activity in human osteosarcoma cell lines and reversal of chemosensitivity
LABORATORY INVESTIGATION
2006 | conference-paper
Multidrug resistance activity in human osteosarcoma cell lines and reversal of chemosensitivity
Modern Pathology
2006 | journal-article
Multidrug resistance activity in human osteosarcoma cell lines and reversal of chemosensitivity
Laboratory Investigation
2006 | journal-article
Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies
Nuclear medicine and biology
2006 | journal-article
Monitoring Multidrug Resistance (MDR) in Osteosarcoma Cell Lines with 99mTc-Sestamibi (MIBI) and 99mTc-Tetrofosmin (Tfs)
European Journal of Nuclear Medicine and Molecular Imaging
2005 | journal-article
Monitoring Multidrug Resistance (MDR) in Osteosarcoma Cell Lines with Tc-99m-Sestamibi (MIBI) and Tc-99m-Tetrofosmin (Tfs)
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2005 | conference-paper
Comparison of the predicted in vivo behaviour of the Sn(II)-APDDMP complex and the results as studied in a rodent model.
2004 | journal-article
Polyethyeneiminomethyl phosphonate (PEI-MP) for se-lectively targeting bone malignancies
European Journal of Nuclear Medicine and Molecular Imaging
2004 | conference-paper
Polyethyeneiminomethyl phosphonate (PEI-MP) for selectively targeting bone malignancies (vol 30, pg S301, 2003)
European Journal of Nuclear Medicine and Molecular Imaging
2004 | journal-article
Uptake and efflux kinetics of Tc-99m-MIBI and Tc-99m-Tetrofosmin in a Pgp-expressing tumour cell line
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2004 | conference-paper
Uptake and efflux kinetics of Tc-99m-MIBI and Tc-99m-Tetrofosmin in a Pgp-expressing tumour cell line
European Journal of Nuclear Medicine and Molecular Imaging
2004 | journal-article
117m Sn and 186 Re radiolabelling of polyethyleniminomethyl phosphonic acid (PEI-MP), followed by in vivo targeting of induced osteosarcoma in nude mice
Nuklearmedizin
2003 | journal-article
99mTc-DMSA (V) as tracer in the imaging of cardiac amyloidosis
Nuclear Medicine Communications
2003 | journal-article
EANM Learning Course on Clinical PET
European Journal of Nuclear Medicine and Molecular Imaging
2003 | journal-article
Selective Tumour Localisation of the Bone-Seeking Radio-pharmaceutical^ 1^ 1^ 7^ mSn (II)-PEI-MP as Studied in Osteosarcoma Containing Mice
JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS
2003 | journal-article
Métodos computacionais no desenvolvimento de radiofármacos para a tomografia por emissão de positrões.
2002 | dissertation-thesis
Métodos computacionais no desenvolvimento de radiofármacos para a tomografia por emissão de positrões.
2002 | dissertation-thesis
Preliminary Studies of Computer Aided Ligand Design for PET
Physiological Imaging of the Brain with PET
2001 | other
Preliminary studies of computer aided ligand design for PET
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
1999 | journal-article
Estratégias Computacionais no Desenvolvimento de Radioligandos para a Tomografia de Emissão de Positrões
Revista Española de Medicina Nuclear
1998 | journal-article
Kur CHANNEL BLOCKERS
Physiology and Pathophysiology of the Islets of Langerhans
1998 | journal-article
Physiology and Pathophysiology of the Islets of Langerhans
1998 | other
Use of Information Technology in the Search for New PET Tracers
Quantitative Functional Brain Imaging with Positron Emission Tomography
1998 | other
Bursting electrical activity generated in the presence of K
Advances in Experimental Medicine and Biology
1997 | book
Bursting electrical activity generated in the presence of KATP channel blockers
Advances in Experimental Medicine and Biology
1997 | journal-article
Bursting electrical activity generated in the presence of KATP channel blockers. Pharmacology, sensitivity to intracellular pH and modulation by glucose metabolism.
1997 | journal-article
II. STIMULUS SECRETION COUPLING: ARE K (ATP) CHANNELS ENOUGH?-B. The Role for K (ATP) Channels-5. Bursting Electrical Activity Generated in the Presence of KAT, Channel Blockers: Pharmacology
Advances in Experimental Medicine and Biology
1997 | journal-article
The use of information technology in the search for new PET tracers
NEUROIMAGE
1997 | journal-article
Bursting electrical activity in pancreatic β-cells: evidence that the channel underlying the burst is sensitive to Ca2+ influx through L-type Ca2+ channels
Pflügers Archiv European Journal of Physiology
1993 | journal-article
ROBALO CORDEIRO AER/GSK 2008 AWARD/PRÉMIO ROBALO CORDEIRO AER/GSK 2008 Nanoradioliposomes molecularly modulated to study the lung deep lymphatic drainage
| data-set
The relation between neuroinflammation, amyloid-β load, grey matter loss and brain activity in visual object recognition regions in Alzheimer's Disease
NeuroImage: Reports
2026 | journal-article
2-[18F]FDG PET/CT identifies metabolic activity linked to myocardial deformation in hypertrophic cardiomyopathy
Meta-Radiology
2025 | journal-article
Molecular targets and the emerging role of copper radionuclides in prostate cancer theranostics
EJNMMI Research
2025 | journal-article
PET/fMRI demonstrates that bariatric surgery may reverse striatal dopaminergic dysfunction in women with obesity
Communications Medicine
2025 | journal-article
Sex-specific cortical networks drive social behavior differences in an autism spectrum disorder model
Translational Psychiatry
2025 | journal-article
GRPR-targeted gold nanoparticles as selective radiotherapy enhancers in glioblastoma
Physics in Medicine & Biology
2025 | journal-article
Unveiling the potential of copper-61 vs. gallium-68 for SSTR PET imaging
European Journal of Nuclear Medicine and Molecular Imaging
2025 | journal-article
First performance evaluation of easyPET.3D, a high-resolution and cost-effective benchtop preclinical PET scanner
EJNMMI Physics
2025 | journal-article
Is Copper-61 the New Gallium-68? Automation and Preclinical Proof-of-Concept of 61Cu-Based Radiopharmaceuticals for Prostate Cancer Imaging
Pharmaceuticals
2025 | journal-article
177Lu-Trastuzumab Radionuclide Therapy: an Effective Approach for Resistant Brain Metastases in HER2+ Breast Cancer
2025 | preprint
Evidence for Neuroplasticity in the Human Brain in Health and Disease: A Systematic Review Focusing on Molecular Imaging Using PET
Neural Plasticity
2025 | journal-article
Improved Production of Novel Radioisotopes with Custom Energy Cyclone® Kiube
Instruments
2024 | journal-article
Purification of Copper Radioisotopes for Medical Applications: Chromatographic Methods and Challenges
Separation & Purification Reviews
2024 | journal-article
Improved Chemical and Radiochemical Synthesis of Neuropeptide Y Y2 Receptor Antagonist N-Methyl-JNJ-31020028 and Preclinical Positron Emission Tomography Studies
Pharmaceuticals
2024 | journal-article
Neurotensin (8-13) and Neuromedin N Neuropeptides Radiolabelling with Copper-64 Produced on Solid or Liquid Targets
Molecules
2024 | journal-article
Development and Testing of an MRI-Compatible Immobilization Device for Head and Neck Imaging
2024 | book-chapter
11C-carboxylations using Grignard reactions for the preparation of [carbonyl 11C]WAY-100635 and [1-11C]Sodium Acetate
2nd CIBIT Meeting
2023 | conference-poster
Negative correlation between cortical tryptophan metabolism and E/I balance in a genetic mouse model of autism spectrum disorders
2nd CIBIT Meeting
2023 | conference-poster
Fully Automated Production of [68Ga]GaFAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets
International Journal of Molecular Sciences
2023 | journal-article
Fully Automated Production of [68Ga]FAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets
2023 | preprint
GMP Production of 89Zr-DFO-Pembrolizumab for Immuno-PET: predicting response in non-small lung cancer
EANM
2023 | conference-poster
Effects of successful percutaneous coronary intervention of chronic total occlusions with demonstrable viability or ischemia: A protocol for a systematic review
2023 | preprint
Imaging platforms to dissect the in vivo communication, biodistribution and controlled release of extracellular vesicles
Journal of Controlled Release
2023 | journal-article
Evaluating Blood-Brain Barrier Permeability Changes during Premetastatic Niche Formation for HER2+ Breast Cancer Brain Metastasis
EACR 2023 Congress
2023 | conference-poster
Antibody and Nanobody Radiolabeling with Copper-64: Solid vs. Liquid Target Approach
Molecules
2023 | journal-article
GMP Production of Copper-64 for antibody and nanobody radiolabeling: liquid vs solid target
25th iSRS
2023 | conference-poster
Textural properties of microglial activation in Alzheimer's disease as measured by (R)-[11C]PK11195 PET
Brain Communications
2023 | journal-article
Synaptic density marker, SV2A, is reduced in autistic adults
INSAR meeting 2023 - International Society for Autism Research
2023 | conference-poster
A neurostimulation and multimodal molecular imaging study of the interhemispheric inhibition/excitation imbalance in stroke
5th International Brain Stimulation Conference
2023 | conference-poster
Imaging of brain tryptophan metabolism and 5-HT1A receptor density in the TSC2 mouse model: Preliminary results
1º CIBIT Anual Meeting
2022 | conference-poster
89Zr-immuno-PET imaging: from liquid target production to imaging
Nuclear Medicine and Biology
2022 | journal-article
Impact of HER2+ brain-tropic breast cancer cells in blood-brain barrier permeability during the pre-metastatic niche formation
Champalimaud Research Symposium 2022
2022 | conference-poster
GMP Production of 89Zr-DFO-Trastuzumab: from chemistry to the clinic
New Modalities in Cancer Imaging and Therapy
2022 | conference-poster
Trastuzumab-resistant HER2+ Brain Tropic Breast Cancer Cells Disrupt the Blood-Brain Barrier: a Potential Route for Brain Drug Delivery
5th ASPIC International Congress
2022 | conference-poster
PET Imaging of the Neuropeptide Y System: A Systematic Review
Molecules
2022 | journal-article
Production of GMP-Compliant Clinical Amounts of Copper-61 Radiopharmaceuticals from Liquid Targets
Pharmaceuticals
2022 | journal-article
Bringing personalized medicine to the next level: RANKL immuno-PET imaging using [64Cu]Cu-NOTA-anti-RANKL-Fab fragments
Nuclear Medicine and Biology
2022 | journal-article
Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments
Pharmaceutics
2022 | journal-article
An RPC-PET brain scanner demonstrator: first results
ArXiv
2022 | journal-article
Bringing personalized medicine to the next level: RANKL immuno-PET imaging using [64Cu]Cu-NOTA-anti-RANKL-Fab fragments
Nuclear Medicine and Biology
2022 | journal-article
Cardiac microcalcification burden: Global assessment in high cardiovascular risk subjects with Na[18F]F PET-CT
Journal of Nuclear Cardiology
2022 | journal-article
Combined Structural MR and Diffusion Tensor Imaging Classify the Presence of Alzheimer's Disease With the Same Performance as MR Combined With Amyloid Positron Emission Tomography: A Data Integration Approach
Frontiers in Neuroscience
2022 | journal-article
Copper-61 as an alternative to Gallium-68 for radiopharmaceutical production: feasibility study and scale-up for clinical doses
Nuclear Medicine and Biology
2022 | journal-article
Mitochondrial and redox modifications in early stages of Huntington's disease
Redox Biology
2022 | journal-article
Mitochondrial and redox modifications in early stages of Huntington¿s disease
redox modifications in early stages of Huntington¿s disease¿. Preprint
2022 | journal-article
Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung Cancer
Cancers
2022 | journal-article
Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis
Small
2022 | journal-article
Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals
EJNMMI Radiopharmacy and Chemistry
2022 | journal-article
Stable [64Cu]-labelled phthalocyanine choline bioconjugate for development of a potential cancer PET probe. In vivo biodistribution evaluation
Journal of Porphyrins and Phthalocyanines
2022 | journal-article
Ventilador mecânico invasivo de emergência resistente e de fácil manutenção
Revista Brasileira de Terapia Intensiva
2022 | journal-article
Zr-89-immuno-PET imaging: from liquid target production to imaging
2022 | conference-poster
Texture Quantification Parameters for Alzheimer's disease diagnosis measured by 11C- (R)- PK11195 PET images
European Journal of Nuclear Medicine and Molecular Imaging - EANM2021 - Annual Congress of the European Association of Nuclear Medicine
2021 | conference-paper
Nanobody-Based Theranostic Agents for HER2-Positive Breast Cancer: Radiolabeling Strategies
International Journal of Molecular Sciences
2021 | journal-article
Automatic classification of idiopathic Parkinson’s disease and atypical Parkinsonian syndromes combining [11C]raclopride PET uptake and MRI grey matter morphometry
Journal of Neural Engineering
2021 | journal-article
NON-INVASIVE SYSTEM FOR MEASURING THE ARTERIAL INPUT FUNCTION FOR PET IMAGING
2021 | patent
Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA
EJNMMI Radiopharmacy and Chemistry
2021 | journal-article
A link between synaptic plasticity and reorganization of brain activity in Parkinson's disease
Proceedings of the National Academy of Sciences
2021 | journal-article
Investigating the Spatial Associations Between Amyloid-β Deposition, Grey Matter Volume, and Neuroinflammation in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
2021 | journal-article
Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA (vol 6, 11, 2021)
EJNMMI Radiopharmacy and Chemistry
2021 | journal-article
Anticancer Activity and Mode of Action of Copper(II)-Bis(thiosemicarbazonato) Complexes with Pendant Nitrogen Heterocycles
European Journal of Inorganic Chemistry
2021 | journal-article
Copper-61 from liquid targets: optimized purification for GMP labelling
Nuclear Medicine and Biology
2021 | journal-article
Preclinical assessment of nanoparticles conjugated with Cu-64-DOTA-PEG-BBN targeting gastrin-releasing peptide receptors
Journal of Nuclear Medicine
2021 | journal-article
Securing Gallium-68 availability with liquid target production on mid-energy cyclotrons: Users' experience and scaling up
European Journal of Nuclear Medicine and Molecular Imaging
2021 | journal-article
Texture Quantification Parameters for Alzheimer's disease diagnosis measured by 11C-(R)-PK11195 PET images
European Journal of Nuclear Medicine and Molecular Imaging
2021 | journal-article
Trimodal Contrast Agents for MRI and Optical Imaging
European Journal of Clinical Investigation
2021 | journal-article
In Vivo Tracking of Extracellular Vesicles by Nuclear Imaging: Advances in Radiolabeling Strategies
International Journal of Molecular Sciences
2020 | journal-article
Copper-64 Chloride Exhibits Therapeutic Potential in Three-Dimensional Cellular Models of Prostate Cancer.
Frontiers in molecular biosciences
2020 | journal-article
GMP automated purification of copper-61 produced in cyclotron liquid targets: methodological aspects.
Current radiopharmaceuticals
2020 | journal-article
Overreduced intracellular state detected in Cu-ATSM brain imaging and fibroblasts from prodromal Huntington disease carriers
European Journal of Clinical Investigation
2020 | journal-article
Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target
Medical Oncology
2020 | journal-article
Prototype of an affordable pressure-controlled emergency mechanical ventilator for COVID-19
2020 | preprint
Aortic valve microcalcification and cardiovascular risk: an exploratory study using sodium fluoride in high cardiovascular risk patients.
The international journal of cardiovascular imaging
2020 | journal-article
Preconditioning mice with osteosarcoma cells-derived secretome promote tumour cells engraftment and lung metastasis development
Tumor Microenvironment (EACR-AACR Basic and Translational Research Conference in partnership with ASPIC)
2020 | conference-poster
Copper-64 based Radiopharmaceuticals as Potential Theranostic Agents
European Journal of Nuclear Medicine and Molecular Imaging
2020 | journal-article
Does global molecular calcium score have a role in HFpEF evaluation?
European Journal of Heart Failure
2020 | journal-article
Overreduced intracellular state detected in Cu-ATSM brain imaging and fibroblasts from prodromal Huntington disease carriers
European Journal of Clinical Investigation
2020 | journal-article
Renal artery wall 18F-NaF activity and glomerular filtration rate: an exploratory analysis in a high cardiovascular risk population
Nuclear medicine communications
2020 | journal-article
Synthesis Optimisation of High Specific Activity Carbon-11 Radiopharmaceuticals for Brain PET Studies
2020 | dissertation-thesis
Secretome derived from osteosarcoma (OS) cells promote tumour cell colonization and lung metastasis formation in pre-treated mice
CIBB Meeting 2019 - Universidade de Coimbra
2019 | conference-poster
Asymmetric Synthesis of a promising [18F]F-DOPA Precursor
XXV Encontro Galego-Portugês de Química, Santiago de Compostela
2019 | conference-poster
Automated microwave-assisted synthesis for PET radiochemistry
XXV Encontro Galego-Portugês de Química, Santiago de Compostela
2019 | conference-poster
Improved nucleophilic synthesis of [18F]F-DOPA using microwave technology
XXV Encontro Galego-Portugês de Química, Santiago de Compostela
2019 | conference-poster
Osteosarcoma-released bioactive factors facilitate lung metastasis by regulating cell adhesion
Seed and Soil: mechanisms of metastasis (2nd joint EACR-MRS conference)
2019 | conference-poster
New Cu-ATSM and Cu-GTSM Derivatives for Cancer Theranostics
NOVA BIOPHYSICA International Congress
2019 | conference-abstract
Potenciais alvos terapêuticos na leucemia mieloblástica aguda - glicólise ou oxidação fosforilativa?
1º Encontro Nacional de Jovens Investigadores em Oncologia
2019 | conference-poster
Glycolysis versus oxidative phosphorylation ¿ Potential therapeutic targets in AML
24º European Hematology Association Congress
2019 | conference-poster
GMP Production of Gallium-68 from a Cyclotron Using Liquid Targets: Regulatory Aspects
22nd International Symposium on Radiopharmaceutical Sciences
2019 | conference-poster
Impact of neurofibromatosis type 1 on early postnatal development: a behavioral approach.
XVI Meeting of the Portuguese Society for Neurocience
2019 | conference-poster
Neural basis for adult cognitive deficits in neurofibromatosis type 1 animal model: Relevance for autism spectrum disorders.
XVI Meeting of the Portuguese Society for Neurocience
2019 | conference-poster
The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing.
Translational medicine @ UniSa
2019 | journal-article
A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss
Human Molecular Genetics
2019 | journal-article
A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles
Nanoscale
2019 | journal-article
A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles
2019 | journal-article
Activated Gold Nanoparticles Conjugated with 68Ga-DOTA-PEG(4)-BBN(7-14) for Targeting Tumours Expressing GRP Receptors
European Journal of Nuclear Medicine and Molecular Imaging
2019 | journal-article
Cardiovascular risk, aortic valve microcalcification and vascular microcalcification: is there a link?
European Heart Journal
2019 | journal-article
Gd- A nd Eu-Loaded Iron Oxide@Silica Core-Shell Nanocomposites as Trimodal Contrast Agents for Magnetic Resonance Imaging and Optical Imaging
Inorganic Chemistry
2019 | journal-article
Labelling and validation of [61Cu]DOTA-NOC for somatostatin receptors imaging
2019 | dissertation-thesis
New chimeric peptides selectively inhibit APPß cleavage decreasing Aß formation and accumulation in AD models
14th International Conference on Alzheimer's & Parkinson's Diseases, Lisbon, Portugal
2019 | conference-poster
PET imaging and in vivo bio-distribution of small extracellular vesicles
European Journal of Clinical Investigation
2019 | journal-article
THE REFERENCE SITE COLLABORATIVE NETWORK OF THE EUROPEAN INNOVATION PARTNERSHIP ON ACTIVE AND HEALTHY AGEING
Translational Medicine @ UniSa
2019 | journal-article
Radiobiological Characterization of 64CuCl2 as a Simple Tool for Prostate Cancer Theranostics
Molecules
2018 | journal-article
Automated Purification of Radiometals Produced by Liquid Targets
Instruments
2018 | journal-article
Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells
Scientific Reports
2018 | journal-article
The excitation/inhibition enigma in a mouse model of the autism spectrum disorder: evidence for distinct phenotypes of hippocampus and prefrontal cortex
11th FENS - Forum of European Neuroscience
2018 | conference-abstract
Therapeutic potential of the metabolic modulator Metformin on osteosarcoma cancer stem-like cells
Cancer Chemotherapy and Pharmacology
2018 | journal-article
Can 11 C-PiB-PET relative delivery R 1 or 11 C-PiB-PET perfusion replace 18 F-FDG-PET in the assessment of brain neurodegeneration?
Journal of Alzheimer's Disease
2018 | journal-article
Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ species
NeuroImage: Clinical
2018 | journal-article
Distributed non-invasive system for measuring the arterial input function in PET
2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings
2018 | conference-paper
Investigação de um detetor não-invasivo para determinar a função de entrada em estudos PET quantitativos
2018 | dissertation-thesis
Optimized non-conventional radioisotopes production with industrial mid-energy cyclotron
European Journal of Nuclear Medicine and Molecular Imaging
2018 | journal-article
qPET: a system for assessing the arterial input function for PET quantification
European Journal of Nuclear Medicine and Molecular Imaging
2018 | journal-article
Deconstructing cancer stem cells: IL-6, G-CSF and Activin-A as mediators of stroma-orchestrated epithelial cells’ dedifferentiation
Cancer Research
2017 | journal-article
Production of copper-64 and gallium-68 with a medical cyclotron using liquid targets
Modern Physics Letters A
2017 | journal-article
Atherosclerotic plaque metabolism in high cardiovascular risk subjects - A subclinical atherosclerosis imaging study with 18F-NaF PET-CT.
2017 | journal-article
Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes.
2017 | journal-article
Assessment of atherosclerotic plaque calcification using F18-NaF PET-CT.
2017 | journal-article
Comparação entre a PET/CT cerebral com 18F-FDG e a fase de perfusão da PET/CT com 11C-PIB
XVI Congresso Nacional de Medicina Nuclear
2017 | conference-abstract
Cyclotron production of Ga-68 for human use from liquid targets: From theory to practice
AIP Conference Proceedings
2017 | conference-paper
Fast and cost-effective cyclotron production of 61Cu using a natZn liquid target: an opportunity for radiopharmaceutical production and R&D
Dalton Transactions
2017 | journal-article
GMP Production of Gallium-68 from a Cyclotron Using Liquid Targets: Regulatory Aspects
Journal of Labelled Compounds
2017 | journal-article
Selective internal radiation therapy: review of the standard operating procedure for selective internal radiation therapy using SIR-Spheres microspheres labelled with Yttrium 90
2017 | dissertation-thesis
Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: In vivo neurospectroscopy and molecular evidence for regional phenotypes
Molecular Autism
2017 | journal-article
Redox and mitochondrial function switches in striatum and cortex of pre-symptomatic and symptomatic Huntington's Disease mouse model
XIX National Congress of Biochemistry
2016 | conference-poster
Redox and mitochondrial functional switches in striatum and cortex of pre-symptomatic and symptomatic Huntington¿s disease mouse model
XIX National Congress of Biochemistry by the Portuguese Society of Biochemistry
2016 | conference-poster
Redox changes and bioenergetic defects in striatum and and cortex of pre-symptomatic and symptomatic Huntington's Disease mice
Society for Neuroscience 46th annual meeting
2016 | conference-poster
Redox changes and bioenergetic defects in striatum and cortex of pre-symptomatic and symptomatic Huntington disease mice.
46th Annual Meeting of Society for Neuroscience (SFN)
2016 | conference-poster
Production of 68Ga in a mid-energy cyclotron: the solution is in the target
Endocrine Abstracts
2016 | journal-article
GABA deficiency in NF1: A multimodal [11C]-flumazenil and spectroscopy study.
2016 | journal-article
18th European Symposium on Radiopharmacy and Radiopharmaceuticals: Salzburg, Austria. 7-10 April 2016.
EJNMMI radiopharmacy and chemistry
2016 | journal-article
Process for producing gallium-68 through the irradiation of a solution target
2016 | other
Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/β-catenin signaling.
2016 | journal-article
68Ga-PSMA PET/CT in Biochemical Relapsed Prostate Cancer Initial Experience
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2016 | conference-paper
68Ga-PSMA PET/CT in Biochemical Relapsed Prostate Cancer Initial Experience
European Journal of Nuclear Medicine and Molecular Imaging
2016 | journal-article
New BACE1 inhibitors decrease Aß production and accumulation in the 3xtg-AD mouse model
XIX National Congress of Biochemistry
2016 | conference-abstract
Pet examination of the monoamine transporter with 11c-beta-cit
Movement Disorders
2016 | journal-article
Production of 68Ga in a mid-energy cyclotron: the solution is in the target
2016 | journal-article
Synthesis of (R)-[N-Methyl-11C]PK11195
Radiochemical Syntheses
2015 | other
AN ULTRA-HIGH RESOLUTION PRECLINICAL POSITRON EMISSION TOMOGRAPHY SCANNER
IEEE Portuguese Meeting on Bioengineering (ENBENG)
2015 | conference-paper
An ultra-high resolution preclinical positron emission tomography scanner
Bioengineering (ENBENG), 2015 IEEE 4th Portuguese Meeting on
2015 | conference-paper
Desenvolvimento de um modelo dosimétrico baseado em medidas de área
2015 | dissertation-thesis
GMP production of 68Ga-labelled DOTA-NOC on IBA Synthera
Journal of Radioanalytical and Nuclear Chemistry
2015 | journal-article
Optimization and Validation of [N-13]-NH3 Production for Clinical Studies of Positron Emission Tomography in the Evaluation of Myocardial Perfusion
IEEE Portuguese Meeting on Bioengineering (ENBENG)
2015 | conference-paper
Optimization and validation of [13N]-NH
Proceedings - 2015 IEEE 4th Portuguese Meeting on Bioengineering, ENBENG 2015
2015 | conference-paper
Radiochemical Syntheses, Volume 2: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production
2015 | other
Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutic Agents
Journal of Heterocyclic Chemistry
2015 | journal-article
Synthesis and biological distribution study of a new carbon-11 labeled porphyrin for PET imaging. Photochemical and biological characterization of the non-labeled porphyrin
Journal of Porphyrins and Phthalocyanines
2015 | journal-article
Synthesis of (R)-[N-Methyl-11C]PK11195
Radiochemical Syntheses
2015 | book-chapter
Synthesis of a new 18F labeled porphyrin for potential application in positron emission tomography. in vivo imaging and cellular uptake
RSC Advances
2015 | journal-article
The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ
Immunology
2015 | journal-article
Assessing GBM-induced microglia activation with [11C]PK11195
EMIM 2014 9th European Molecular Imaging Meeting
2014 | conference-paper
Estudo combinado de PET com [11C]PiB e [18F]FDG na avaliação de doença de Alzheimer
2014 | dissertation-thesis
GABA alterations in patients with Neurofibromatosis type 1: a multimodal 11C-Flumazenil PET and MRS study
WMIC 2014 World Molecular Imaging Congress
2014 | conference-paper
GMP Production of Gallium-68 Peptides on a Commercial Synthesizer
ESRR'14 - 17th European Symposium on Radiopharmacy and Radiopharmaceuticals
2014 | conference-paper
Importância da [11C]-Racloprida no diagnóstico de Síndromes Parkinsónicos com tomografia por emissão de positrões (PET)
2014 | dissertation-thesis
Inflammatory Microenvironment Supports Stem-like Phenotype in Glioblastoma: Cellular Studies with 11C-PK11195
WFNMB 2014 11th Congress of the World Federation of Nuclear Medicine and Biology
2014 | conference-paper
Optimização e Validação da Produção de [13n]-Nh3 para Estudos Clínicos de Tomografia por Emissão de Positrões na Avaliação da Perfusão Miocárdica
2014 | dissertation-thesis
Síntese de macrociclos tetrapirrólicos fluorados. Desenvolvimento de potenciais marcadores para tomografia por emissão de positrões
2014 | dissertation-thesis
Radiosynthesis and in vivo evaluation of a ¹⁸F-labelled styryl-benzoxazole derivative for β-amyloid targeting.
2013 | journal-article
Synthesis of new 18F and 11C porphyrins and their potential application fo in vivo Moleucar Imaging using PET technique
18th European Symposium on Organic Chemistry
2013 | conference-poster
Automated 68Ga-DOTA-NOC production using a commercial synthesizer
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
2013 | conference-paper
Automated 68Ga-DOTA-NOC production using a commercial synthesizer
Journal of Labelled Compounds and Radiopharmaceuticals
2013 | journal-article
Cyclotron Production of 68Ga using a 68Zn-based liquid target
2013 | dissertation-thesis
Image Analysis in Radiology and Nuclear Medicine Automated Analysis of Morfology and Funtion of the Human Brain
IEEE Portuguese Meeting in Bioengineering (ENBENG)
2013 | conference-paper
Image analysis in radiology and nuclear medicine
Bioengineering (ENBENG), 2013 IEEE 3rd Portuguese Meeting in
2013 | conference-paper
Image analysis in radiology and nuclear medicine
3rd Portuguese Bioengineering Meeting, ENBENG 2013 - Book of Proceedings
2013 | conference-paper
Kur CHANNEL BLOCKERS
Physiology and Pathophysiology of the Islets of Langerhans
2013 | journal-article
Optimisation of Synthesis, Purification and Reformulation of (R)-[N-Methyl-C-11]PKll195 for In Vivo PET Imaging Studies
IEEE Portuguese Meeting in Bioengineering (ENBENG)
2013 | conference-paper
Optimisation of synthesis, purification and reformulation of (R)-[N-Methyl-11C]PK11195 for in vivo PET imaging studies
3rd Portuguese Bioengineering Meeting, ENBENG 2013 - Book of Proceedings
2013 | conference-paper
Production optimization of 68Ga-DOTA-NOC for routine synthesis
Journal of Nuclear Medicine
2013 | journal-article
Radiosynthesis of new 18F-labelled meso-tetraphenylporphyrins as potential tracers for in vivo molecular imaging with PET
Journal of Labelled Compounds and Radiopharmaceuticals
2013 | journal-article
Radiosynthesis of new F-18-labelled meso-tetraphenylporphyrins as potential tracers for in vivo molecular imaging with PET
Journal of Labelled Compounds & Radiopharmaceuticals
2013 | journal-article
Synthesis of optimization of [11C] Pittsburgh compound B by the captive solvent method
2013 | dissertation-thesis
473 Hexavalent Chromium, Cancer Stem Cells and Dedifferentiation –a View to a Kill!
European Journal of Cancer
2012 | journal-article
Hexavalent Chromium, Cancer Stem Cells and Dedifferentiation--a View to a Kill!
European Journal of Cancer
2012 | journal-article
Neurodevelopmental Effects of High Magnetic Fields in the Development of an Intact Living Organism: Caenorhabditis elegans
WMIC'12 World Molecular Imaging Congress
2012 | conference-paper
Neuronal and developmental effects of high magnetic fields in the development of an intact living organism: Ceanorhabditis elegans
2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012
2012 | conference-paper
Optimisation of synthesis, purification and reformulation of (R)-[N-methyl-¹¹C] PK11195 for in vivo PET imaging studies
2012 | dissertation-thesis
Optimization of [18F]-FDG production with terminal sterilization by autoclave
Journal of Nuclear Medicine
2012 | journal-article
Optimization of [18F]-FDG production with terminal sterilization by autoclave
Journal of Nuclear Medicine
2012 | journal-article
Positron emitting tracers in pre-clinical drug development
Current Radiopharmaceuticals
2012 | journal-article
Synthesis optimization of pittsburgh compound B by the captive solvent method
2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012
2012 | conference-paper
Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line.
2012 | journal-article
Synthesis of carbon-11 labeled porphyrins as potential cancer biomarkers for PET imaging
XXIII National meeting of Portuguese Society of Chemistry
2011 | conference-poster
Molecular imaging with SPECT as a tool for drug development.
2011 | journal-article
Elucidation of the drug resistance mechanisms of osteosarcoma cancer stem cells with PET tracers
1st Portuguese Meeting in Biomedical Engineering, ENBENG 2011
2011 | conference-paper
Molecular imaging with SPECT and PET in exploratory investigational new drug studies
Drugs of the Future
2011 | journal-article
Molecular imaging with SPECT and PET in exploratory investigational new drug studies
Drugs of the Future
2011 | journal-article
Nanoradioliposomes molecularly modulated to study the lung deep lymphatics drainage.
2010 | journal-article
Aspectos do controlo da qualidade da fluodesoxiglucose num laboratório de produção
Acta Médica Portuguesa
2010 | journal-article
Assessing metabolic activity of Cancer Stem Cells during differentiation with [18 F] FDG
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2010 | conference-paper
Assessing metabolic activity of cancer stem cells during differentiation with [F-18]FDG
European Journal of Nuclear Medicine and Molecular Imaging
2010 | journal-article
Cancer stem cell populations in osteosarcoma: implications for [18F] FDG uptake and response to therapy
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2010 | conference-paper
Cancer stem cell populations in osteosarcoma: implications for [18F]FDG uptake and response to therapy
European Journal of Nuclear Medicine and Molecular Imaging
2010 | journal-article
Nanorradiolipossomas modulados molecularmente para estudar a drenagem linfática profunda pulmonar
Revista Portuguesa de Pneumologia
2010 | journal-article
Osteosarcoma contains a subpopulation of cancer stem-like cells that are highly resistant to radiotherapy.
2010 | journal-article
Radiopharmaceuticals
Nuclear Medicine Physics. Series: Series in Medical Physics and Biomedical Engineering, ISBN: 978-1-58488-795-9. Taylor & Francis, Edited by J de Lima, pp. 95-132
2010 | journal-article
Role of Cancer Stem Cells in [18F]FDG Uptake and Therapy Response in Osteosarcoma
2010 World Molecular Imaging Congress
2010 | conference-paper
Síntese de [18F]-FDG no módulo synthera
Acta Médica Portuguesa
2010 | conference-paper
Śıntese e purificação de [11C]-raclopride
Acta Médica Portuguesa
2010 | journal-article
P-glycoprotein versus MRP1 on transport kinetics of cationic lipophilic substrates: a comparative study using [99mTc]sestamibi and [99mTc]tetrofosmin.
2009 | journal-article
Imaging multidrug resistance in osteosarcoma: A pre-clinical approach using an orthotopic animal model
IFMBE Proceedings
2009 | conference-paper
Nanoradioliposomes molecularly modulated to study the lung deep lymphatic drainage
2009 | journal-article
Nanoradioliposomes molecularly modulated to study the lung deep lymphatic drainage,Nanorradiolipossomas modulados molecularmente para estudar a drenagem linfática pulmonar profunda
Revista Portuguesa de Pneumologia
2009 | journal-article
Re and Tc Tricarbonyl Complexes with Established Affinity for 5-HT1A Receptors: a 3D QSAR study
2009 World Molecular Imaging Congress
2009 | conference-paper
Effects of high magnetic fields in the development of the organism Caenorhabditis Elegans
2008 World Molecular Imaging Congress
2008 | conference-paper
Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using 99mTc-sestamibi.
2007 | journal-article
Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using 99mTc-sestamibi
European journal of nuclear medicine and molecular imaging
2007 | journal-article
Molecular imaging of multidrug resistance in an orthotopic model of osteosarcoma
Modern Pathology
2007 | journal-article
Molecular imaging of multidrug resistance in an orthotopic model of osteosarcoma
Laboratory Investigation
2007 | journal-article
[Tc-99m] Sestamibi vs.[Tc-99m] Tetrofosmin for functional assessment of P-glycoprotein and MRP1-mediated drug resistance in SCLC cell lines
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2007 | conference-paper
[Tc-99m]Sestamibi vs. [Tc-99m]Tetrofosmin for functional assessment of P-glycoprotein and MRP1-mediated drug resistance in SCLC cell lines
European Journal of Nuclear Medicine and Molecular Imaging
2007 | journal-article
Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies.
2006 | journal-article
Molecular imaging of multidrug resistance in an orthotopic model of osteosarcoma
EUR J NUCL MED MOL I
2006 | journal-article
Molecular imaging of multidrug resistance in an orthotopic model of osteosarcoma
European Journal of Nuclear Medicine and Molecular Imaging
2006 | journal-article
Multidrug resistance activity in human osteosarcoma cell lines and reversal of chemosensitivity
LABORATORY INVESTIGATION
2006 | conference-paper
Multidrug resistance activity in human osteosarcoma cell lines and reversal of chemosensitivity
Modern Pathology
2006 | journal-article
Multidrug resistance activity in human osteosarcoma cell lines and reversal of chemosensitivity
Laboratory Investigation
2006 | journal-article
Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies
Nuclear medicine and biology
2006 | journal-article
Monitoring Multidrug Resistance (MDR) in Osteosarcoma Cell Lines with 99mTc-Sestamibi (MIBI) and 99mTc-Tetrofosmin (Tfs)
European Journal of Nuclear Medicine and Molecular Imaging
2005 | journal-article
Monitoring Multidrug Resistance (MDR) in Osteosarcoma Cell Lines with Tc-99m-Sestamibi (MIBI) and Tc-99m-Tetrofosmin (Tfs)
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2005 | conference-paper
Comparison of the predicted in vivo behaviour of the Sn(II)-APDDMP complex and the results as studied in a rodent model.
2004 | journal-article
Polyethyeneiminomethyl phosphonate (PEI-MP) for se-lectively targeting bone malignancies
European Journal of Nuclear Medicine and Molecular Imaging
2004 | conference-paper
Polyethyeneiminomethyl phosphonate (PEI-MP) for selectively targeting bone malignancies (vol 30, pg S301, 2003)
European Journal of Nuclear Medicine and Molecular Imaging
2004 | journal-article
Uptake and efflux kinetics of Tc-99m-MIBI and Tc-99m-Tetrofosmin in a Pgp-expressing tumour cell line
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
2004 | conference-paper
Uptake and efflux kinetics of Tc-99m-MIBI and Tc-99m-Tetrofosmin in a Pgp-expressing tumour cell line
European Journal of Nuclear Medicine and Molecular Imaging
2004 | journal-article
117m Sn and 186 Re radiolabelling of polyethyleniminomethyl phosphonic acid (PEI-MP), followed by in vivo targeting of induced osteosarcoma in nude mice
Nuklearmedizin
2003 | journal-article
99mTc-DMSA (V) as tracer in the imaging of cardiac amyloidosis
Nuclear Medicine Communications
2003 | journal-article
EANM Learning Course on Clinical PET
European Journal of Nuclear Medicine and Molecular Imaging
2003 | journal-article
Selective Tumour Localisation of the Bone-Seeking Radio-pharmaceutical^ 1^ 1^ 7^ mSn (II)-PEI-MP as Studied in Osteosarcoma Containing Mice
JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS
2003 | journal-article
Métodos computacionais no desenvolvimento de radiofármacos para a tomografia por emissão de positrões.
2002 | dissertation-thesis
Métodos computacionais no desenvolvimento de radiofármacos para a tomografia por emissão de positrões.
2002 | dissertation-thesis
Preliminary Studies of Computer Aided Ligand Design for PET
Physiological Imaging of the Brain with PET
2001 | other
Preliminary studies of computer aided ligand design for PET
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
1999 | journal-article
Estratégias Computacionais no Desenvolvimento de Radioligandos para a Tomografia de Emissão de Positrões
Revista Española de Medicina Nuclear
1998 | journal-article
Kur CHANNEL BLOCKERS
Physiology and Pathophysiology of the Islets of Langerhans
1998 | journal-article
Physiology and Pathophysiology of the Islets of Langerhans
1998 | other
Use of Information Technology in the Search for New PET Tracers
Quantitative Functional Brain Imaging with Positron Emission Tomography
1998 | other
Bursting electrical activity generated in the presence of K
Advances in Experimental Medicine and Biology
1997 | book
Bursting electrical activity generated in the presence of KATP channel blockers
Advances in Experimental Medicine and Biology
1997 | journal-article
Bursting electrical activity generated in the presence of KATP channel blockers. Pharmacology, sensitivity to intracellular pH and modulation by glucose metabolism.
1997 | journal-article
II. STIMULUS SECRETION COUPLING: ARE K (ATP) CHANNELS ENOUGH?-B. The Role for K (ATP) Channels-5. Bursting Electrical Activity Generated in the Presence of KAT, Channel Blockers: Pharmacology
Advances in Experimental Medicine and Biology
1997 | journal-article
The use of information technology in the search for new PET tracers
NEUROIMAGE
1997 | journal-article
Bursting electrical activity in pancreatic β-cells: evidence that the channel underlying the burst is sensitive to Ca2+ influx through L-type Ca2+ channels
Pflügers Archiv European Journal of Physiology
1993 | journal-article
ROBALO CORDEIRO AER/GSK 2008 AWARD/PRÉMIO ROBALO CORDEIRO AER/GSK 2008 Nanoradioliposomes molecularly modulated to study the lung deep lymphatic drainage
| data-set
