Algoritmi | User | João Filipe da Costa Martins
João Filipe da Costa Martins
João Filipe da Costa Martins
Personal Email
jfmartins@fmed.uc.ptOrcid
0000-0001-7764-286XResearcher ID
FCT Public Key
Ciência ID
C61F-E0B3-BC6AGoogle Scholar
About Me
João Filipe da Costa Martins obtained his PhD in Biomedical Sciences in 2015 from the University of Coimbra. He has been working in Neurosciences, mainly in Vision Sciences. He has published 37 journal articles, mostly in first-quartile journals, with more than 900 citations and an h-index of 16. João has developed his research studies at the University of Coimbra, Portugal; the Vision Institute in Paris, France; the University of Copenhagen, Denmark; and NOVA University Lisbon, Portugal. He has been involved in more than 20 research projects and has been supervising PhD, MSc, and BSc students in Biology, Biochemistry, and Biomedical Engineering. In 2021, João was awarded a Seed Project at Coimbra Institute for Biomedical Imaging and Translational Research, University of Coimbra, as Principal Investigator, to study neuroplasticity mechanisms in animal models of neurodevelopmental differences. His current research interests focus on understanding basic brain physiology, particularly the visual system from the retina to the visual cortex, and how it is modulated by experience such as social interactions. A major goal is to unravel how neurodevelopmental differences affect neuronal processing and plasticity. He is exploring brain stimulation and pharmacotherapies as potential means of ameliorating cognitive deficits. João uses various techniques, ranging from fundamental cellular and molecular biology and microscopy to rodent behavioral tests, in vitro and in vivo electrophysiology, optical coherence tomography, and functional magnetic resonance imaging. His other activities include serving as reviewer for scientific journals in Neuroscience and Vision Science, acting as jury of BSc and MSc degrees, and speaking at Brain Awareness Week dissemination events, including laboratory and school visits.
Publications (38)
Increased susceptibility to kainate‐induced seizures in a mouse model of tuberous sclerosis complex: Importance of sex and circadian cycle
Epilepsia Open
2024 | journal-article
Mapping functional traces of opioid memories in the rat brain
Brain Communications
2024 | journal-article
Functional imaging and neurochemistry identify in vivo neuroprotection mechanisms counteracting excitotoxicity and neurovascular changes in the hippocampus and visual cortex of obese and type 2 diabetic animal models
Journal of Neurochemistry
2023 | journal-article
Neurobehavioral sex-related differences in Nf1+/- mice: female show a 'camouflaging'-type behavior
Biology of Sex Differences
2023 | journal-article
Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease
Frontiers in Aging Neuroscience
2023 | journal-article
Retinal imaging in animal models: Searching for biomarkers of neurodegeneration
Frontiers in Ophthalmology
2023 | journal-article
Sex Differences in Tryptophan Metabolism: A Systematic Review Focused on Neuropsychiatric Disorders
International Journal of Molecular Sciences
2023 | journal-article
Visual Cortical Plasticity: Molecular Mechanisms as Revealed by Induction Paradigms in Rodents
International Journal of Molecular Sciences
2023 | journal-article
Stage-independent biomarkers for Alzheimer's disease from the living retina: an animal study
Scientific Reports
2022 | journal-article
Defining milestones for the study of remyelination using the cuprizone mouse model: How early is early?
Multiple Sclerosis and Related Disorders
2022 | journal-article
Retinal Aging in 3× Tg-AD Mice Model of Alzheimer's Disease
Frontiers in Aging Neuroscience
2022 | journal-article
Transcranial Direct Current Stimulation as an Approach to Mitigate Neurodevelopmental Disorders Affecting Excitation/Inhibition Balance: Focus on Autism Spectrum Disorder, Schizophrenia, and Attention Deficit/Hyperactivity Disorder
Journal of Clinical Medicine
2022 | journal-article
Male sex bias in early and late onset neurodevelopmental disorders: shared aspects and differences in autism spectrum disorder, attention deficit/hyperactivity disorder, and schizophrenia
Neuroscience and Biobehavioral Reviews
2022 | journal-article
Sex-dependent social and repetitive behavior and neurochemical profile in mouse model of autism spectrum disorder
Metabolites
2022 | journal-article
Nanotools for the Treatment of Ocular Diseases
Nanomaterials and Nanotechnology in Medicine
2022 | book-chapter
Longitudinal normative OCT retinal thickness data for wild-type mice, and characterisation of changes in the 3xTg-AD mice model of Alzheimer's disease
Aging
2021 | journal-article
The value of choroidal thickness in diabetic macular oedema is contradictory
Acta Ophthalmologica
2021 | journal-article
Choroidal and retinal structural, cellular and vascular changes in a rat model of Type 2 diabetes
Biomedicine & Pharmacotherapy
2020 | journal-article
Emerging Trends in Nanomedicine for Improving Ocular Drug Delivery: Light-Responsive Nanoparticles, Mesoporous Silica Nanoparticles, and Contact Lenses
ACS Biomaterials Science & Engineering
2020 | journal-article
Inflammatory cells proliferate in the choroid and retina without choroidal thickness change in early Type 1 diabetes
Experimental Eye Research
2020 | journal-article
Characterization of the Retinal Changes of the 3xTg-AD Mouse Model of Alzheimer’s Disease
Health and Technology
2020 | journal-article
Memory and Cognition-Related Neuroplasticity Enhancement by Transcranial Direct Current Stimulation in Rodents: A Systematic Review
Neural Plasticity
2020 | journal-article
Neuropeptide Y system mRNA expression changes in the hippocampus of a type I diabetes rat model
Annals of Anatomy - Anatomischer Anzeiger
2019 | journal-article
Evaluation of markers of outcome in real-world treatment of diabetic macular edema
2018 | journal-article
Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes
Molecular Vision
2018 | journal-article
Impact of type 1 diabetes mellitus and sitagliptin treatment on the neuropeptide Y system of rat retina
Clinical and Experimental Ophthalmology
2018 | journal-article
Opening eyes to nanomedicine: where we are, challenges and expectations on nanotherapy for diabetic retinopathy
Nanomedicine
2017 | journal-article
Viewing the choroid: where We Stand, Challenges and Contradictions in Diabetic Retinopathy and Diabetic Macular Oedema
Acta Ophthalmol
2016 | journal-article
Activation of neuropeptide Y receptors modulates retinal ganglion cell physiology and exerts neuroprotective actions in vitro.
2015 | journal-article
Effects of drugs of abuse on the central neuropeptide Y system.
Addict Biol.
2015 | journal-article
Sildenafil Acutely Decreases Visual Responses in ON and OFF Retinal Ganglion Cells
Invest Ophthalmol Vis Sci
2015 | journal-article
Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection.
Prog Neurobiol.
2014 | journal-article
Taurine provides neuroprotection against retinal ganglion cell degeneration.
PLoS One
2012 | journal-article
Effects of 3,4-Methylenedioxymethamphetamine Administration on Retinal Physiology in the Rat.
PLoS One
2011 | journal-article
Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes.
Diabetes
2010 | journal-article
Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide.
J Neurochem
2008 | journal-article
Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy.
Neuroscience
2008 | journal-article
NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells.
Neurochem Int.
2007 | journal-article
Increased susceptibility to kainate‐induced seizures in a mouse model of tuberous sclerosis complex: Importance of sex and circadian cycle
Epilepsia Open
2024 | journal-article
Mapping functional traces of opioid memories in the rat brain
Brain Communications
2024 | journal-article
Functional imaging and neurochemistry identify in vivo neuroprotection mechanisms counteracting excitotoxicity and neurovascular changes in the hippocampus and visual cortex of obese and type 2 diabetic animal models
Journal of Neurochemistry
2023 | journal-article
Neurobehavioral sex-related differences in Nf1+/- mice: female show a 'camouflaging'-type behavior
Biology of Sex Differences
2023 | journal-article
Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease
Frontiers in Aging Neuroscience
2023 | journal-article
Retinal imaging in animal models: Searching for biomarkers of neurodegeneration
Frontiers in Ophthalmology
2023 | journal-article
Sex Differences in Tryptophan Metabolism: A Systematic Review Focused on Neuropsychiatric Disorders
International Journal of Molecular Sciences
2023 | journal-article
Visual Cortical Plasticity: Molecular Mechanisms as Revealed by Induction Paradigms in Rodents
International Journal of Molecular Sciences
2023 | journal-article
Stage-independent biomarkers for Alzheimer's disease from the living retina: an animal study
Scientific Reports
2022 | journal-article
Defining milestones for the study of remyelination using the cuprizone mouse model: How early is early?
Multiple Sclerosis and Related Disorders
2022 | journal-article
Retinal Aging in 3× Tg-AD Mice Model of Alzheimer's Disease
Frontiers in Aging Neuroscience
2022 | journal-article
Transcranial Direct Current Stimulation as an Approach to Mitigate Neurodevelopmental Disorders Affecting Excitation/Inhibition Balance: Focus on Autism Spectrum Disorder, Schizophrenia, and Attention Deficit/Hyperactivity Disorder
Journal of Clinical Medicine
2022 | journal-article
Male sex bias in early and late onset neurodevelopmental disorders: shared aspects and differences in autism spectrum disorder, attention deficit/hyperactivity disorder, and schizophrenia
Neuroscience and Biobehavioral Reviews
2022 | journal-article
Sex-dependent social and repetitive behavior and neurochemical profile in mouse model of autism spectrum disorder
Metabolites
2022 | journal-article
Nanotools for the Treatment of Ocular Diseases
Nanomaterials and Nanotechnology in Medicine
2022 | book-chapter
Longitudinal normative OCT retinal thickness data for wild-type mice, and characterisation of changes in the 3xTg-AD mice model of Alzheimer's disease
Aging
2021 | journal-article
The value of choroidal thickness in diabetic macular oedema is contradictory
Acta Ophthalmologica
2021 | journal-article
Choroidal and retinal structural, cellular and vascular changes in a rat model of Type 2 diabetes
Biomedicine & Pharmacotherapy
2020 | journal-article
Emerging Trends in Nanomedicine for Improving Ocular Drug Delivery: Light-Responsive Nanoparticles, Mesoporous Silica Nanoparticles, and Contact Lenses
ACS Biomaterials Science & Engineering
2020 | journal-article
Inflammatory cells proliferate in the choroid and retina without choroidal thickness change in early Type 1 diabetes
Experimental Eye Research
2020 | journal-article
Characterization of the Retinal Changes of the 3xTg-AD Mouse Model of Alzheimer’s Disease
Health and Technology
2020 | journal-article
Memory and Cognition-Related Neuroplasticity Enhancement by Transcranial Direct Current Stimulation in Rodents: A Systematic Review
Neural Plasticity
2020 | journal-article
Neuropeptide Y system mRNA expression changes in the hippocampus of a type I diabetes rat model
Annals of Anatomy - Anatomischer Anzeiger
2019 | journal-article
Evaluation of markers of outcome in real-world treatment of diabetic macular edema
2018 | journal-article
Subtle thinning of retinal layers without overt vascular and inflammatory alterations in a rat model of prediabetes
Molecular Vision
2018 | journal-article
Impact of type 1 diabetes mellitus and sitagliptin treatment on the neuropeptide Y system of rat retina
Clinical and Experimental Ophthalmology
2018 | journal-article
Opening eyes to nanomedicine: where we are, challenges and expectations on nanotherapy for diabetic retinopathy
Nanomedicine
2017 | journal-article
Viewing the choroid: where We Stand, Challenges and Contradictions in Diabetic Retinopathy and Diabetic Macular Oedema
Acta Ophthalmol
2016 | journal-article
Activation of neuropeptide Y receptors modulates retinal ganglion cell physiology and exerts neuroprotective actions in vitro.
2015 | journal-article
Effects of drugs of abuse on the central neuropeptide Y system.
Addict Biol.
2015 | journal-article
Sildenafil Acutely Decreases Visual Responses in ON and OFF Retinal Ganglion Cells
Invest Ophthalmol Vis Sci
2015 | journal-article
Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection.
Prog Neurobiol.
2014 | journal-article
Taurine provides neuroprotection against retinal ganglion cell degeneration.
PLoS One
2012 | journal-article
Effects of 3,4-Methylenedioxymethamphetamine Administration on Retinal Physiology in the Rat.
PLoS One
2011 | journal-article
Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes.
Diabetes
2010 | journal-article
Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide.
J Neurochem
2008 | journal-article
Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy.
Neuroscience
2008 | journal-article
NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells.
Neurochem Int.
2007 | journal-article